Is it permissible for one to shake hands with his uncle`s daughter?
No, it isn`t because he is a non-Mahram (Marriageable) to her.
Is the prayer of someone who didn`t face Quibla (Ka`ba direction) valid?
All perfect praise be to Allah,The Lord of The Worlds. Facing the Quibla is a condition for the validity of prayer, and the prayer of the person who hadn`t faced the direction of the Quibla is invalid, and he is obliged to repeat it. And Allah Knows Best.
Is it permissible to include others in the reward of one`s sacrifice?
In the Name of Allah, and may peace and blessings be upon our Master, the Messenger of Allah.
It is permissible for the person offering an Udhiyah (sacrificial offering) to include others in the spiritual reward of the sacrifice. However, it is not permissible for multiple people to jointly share the purchase price of a single sheep or goat, unless one person gifts the money to the other.
It is stated in Mughni al-Muhtaj (6/137) by Al-Khatib al-Shirbini:
"If a person includes someone else in the reward of his sacrifice and slaughters it on his own behalf, it is permissible."
It should be carefully noted that including someone else in the reward of one's sacrifice is completely distinct from offering a sacrifice on behalf of someone else. And Allah the Almighty Knows Best.
When does the time for the Fajr prayer begin?
Praise be to Allah, and peace and blessings be upon our Master, the Messenger of Allah.
The time for the Fajr prayer begins once the Mu’adhin starts the second Adhan (Al-Adhan al-Thani), and not after the first Adhan. And Allah the Exalted knows best.