Should nail polish be removed before making ablution?
Yes, it should be removed because it prevents water from reaching the nails.
Does the clipping of nails nullify ablution?
No, it does not, and it is preferable to wash the hands afterwards.
What is the ruling on performing istinja' with perfumed tissues or a tissue moistened with water?
Performing istinja' with perfumed or moistened tissues is not sufficient if they are not dry, due to the moisture on them reaching the impurity, which increases its spread rather than reducing it. Then, to remove the impurity, one must use pure water. And Allah the Almighty knows best.
What is the ruling on using eye drops while fasting?
Eye drops do not break the fast, even if the taste reaches the throat, because the eye is not an open passage to the body cavity.