Is it permissible for one to shake hands with his uncle`s daughter?
No, it isn`t because he is a non-Mahram(Marriageable) to her.
Is it permissible for a wife to leave her house without asking her husband?
It is impermissible for the wife to leave her house without asking her husband except for a sound reason.
There is a job opportunity in the Nuns Hospital. Is it allowed for me to take this job given the difficult living conditions and the high rate of unemployment?
All perfect praise be to Allah, The Lord of The Worlds, and may His Peace and Blessings be upon our Prophet Muhammad and upon all of his family and companions.
If your work is lawful and has no effect on your beliefs, then there is no sin on you and do your best to represent the true face of Islam. And Allah The Almighty Knows Best.
What is the ruling on working for orphans' institution?
Praise be to Allah the Lord of the Worlds. May His peace and blessings be upon our Prophet Mohammad and upon all his family and companions.
There is no sin in working for orphans` institution. And Allah The Almighty Knows Best.