Is it permissible for a person to sever ties with his sister because her husband had quit prayer and done him harm?
A sister is a blood-relative and maintaining blood-relations is mandatory in Islam. As regards her husband, he should be invited to the way of Allah with wisdom and beautiful preaching.
Is it permissible for one to give the Zakah(obligatory charity) to his indebted brother?
It is permissible for one to give the Zakah to his indebted , or poor brother.
Is the maternal uncle of one`s mother a Maharam?
All perfect praise be to Allah the Lord of The Worlds. May His blessings and peace be upon our Prophet Mohammad and upon all his family and companions.
Mother`s maternal uncle is a mahram. And Allah The Almighty Knows Best.
* In Islam, a mahram is a member of one's family with whom marriage would be considered haram, concealment purdah, or concealment of the body with hijab, is not obligatory; and with whom, if he is an adult male, she may be escorted during a journey, although an escort may not be obligatory.
What should the man, whose wife wasn`t on good terms with his mother, do?
Both the mother and the wife have rights on the man in question; therefore, each should be given her rights justly, and he should resort to wisdom to please both of them and make reconciliation.